Research Publications
Bio Nova's technology has a strong scientific background as evidenced by this selection of research publications:
Retention of endothelium on ovine collagen biomatrix vascular conduits under physiological shear stress
I.E. Birchall, V.W.K. Lee, V. Ketharanathan (2001)
Biomaterials 22:3139-3144
Adherence of Human Saphenous Vein Endothelial Cell Monolayers to Tissue-Engineered Biomatrix Vascular Conduits
I.E. Birchall, P.L. Field, V. Ketharanathan (2001)
J. Biomed. Mater. Res. 56:437-443
Effects of Mesh Modification on the Structure of a Mandrel-Grown Biosynthetic Vascular Prosthesis
J.A.M. Ramshaw, F. Casagranda, J.F. White, G.A. Edwards, J.A. Hunt, D.F. Williams, J.A. Werkmeister (1999)
J. Biomed. Mater. Res. 47:309-315
In Vivo Evaluation of Modified Mandrel Grown Vascular Prostheses
J.A. Werkmeister, G.A. Edwards, J.F. White, F. Casagranda, J.A. Hunt, D.F. Williams, J.A. Ramshaw (1999)
J. Biomed. Mater. Res. 47:316-323
Endothelialization of Biosynthetic Vascular Prostheses after Laser Perforation
M. Grabenwoger, F. Fitzal, J Sider, C. Cseko, H.Bergmeister,H. Schima, W. Husinsky, P. Bock, E. Wolner (1998)
Ann. Thorac. Surg. 66:S110-114
Tissue-Polymer Composite Vascular Prosthesis
J. Ramshaw, J. Werkmeister, G. Edwards (1995)
In Encyclopedic Handbook of Biomaterials and Bioengineering, part B, vol 2, pp 953-978. Marcel Dekker, Inc, New York, 1995.
Evaluation of the Omniflow Collagen-Polymer Vascular Prosthesis
J.A. Werkmeister, J.F. White, J.A. Ramshaw (1994)
Med. Prog. Technol. 20:231-242
Evaluation of Alternative Glutaraldehyde Stabilization Strategies for Collagenous Biomaterials.
F. Casagranda, J.A. Werkmeister, J.A. Ramshaw, G. Ellender (1994)
J. Mater. Sci. Mater. Med. 5:332-337
Collagen Organization in an Oriented Fibrous Capsule
B. Brodsky, J.A.M. Ramshaw (1994)
Int. J. Biol. Macromol. 16:27-30
Stratigraphic Evaluation of the Collagen Surrounding a Biomaterial Implant
J.A.M. Ramshaw, F. Casagranda, J.F. White, J.A. Werkmeister (1994)
Clin. Mater. 16:9-13
Biologic vascular grafts in the venous position
Y. Tomizawa, M.R. Moon, Y. Noishiki (1994)
J Thorac. Cardiovasc. Surg. 107:948-949
[comment on J. Thorac. Cardiovasc. Surg. (1991) 102:440-447]
Structural Analysis of a Collagen-Polyester Composite Vascular Prosthesis
J.F. White, J.A. Werkmeister, G.A. Edwards, J.A.M. Ramshaw (1993)
Clin. Mater. 14:271-276
Monoclonal Antibodies to Type VI Collagen Demonstrate New Tissue Augmentation of a Collagen-based Biomaterial Implant
J.A. Werkmeister, T.A. Tebb, J.F. White, J.A. M. Ramshaw (1993)
J. Histochem. Cytochem. 41:1701-1706
Development of an Ovine Collagen-Based Composite Biosynthetic Vascular Prosthesis
G.A. Edwards, G. Roberts (1992)
Clin. Mater. 9:211-213
An experimental study to examine the patency and tissue response of two types of biosynthetic graft used as a replacement for porcine inferior vena cava
G.B. Ratto, A. Leprini, P. Romano, G. Fantino, E. Tassara, D. Zaccheo (1992)
J. Cardiovasc. Surg. 33:700-704
In Vivo Assessment of Neovascularization and Incorporation of Prosthetic Vascular Biografts
M.D. Menger, F. Hammersen, K. Messmer (1992)
Thorac. Cardiovasc. Surg. 40:19-25
Evaluation of Collagen Turnover and Structural Stability in Long Term Implants of a Collagen-based Vascular Prosthesis
J.A. Werkmeister, G.A. Edwards, V. Glattauer, T.A. Tebb, F. Casagranda, G. Roberts, J.A.M. Ramshaw (1992)
In Advances in Biomaterials, vol 10, pp 287-291. Elsevier Science Publishers, Amsterdam, 1992
Glutaraldehyde-tanned mandril-grown grafts as venous substitutes
G.B. Ratto, P. Romano, M. Truini, M. Frascio, S. Rovida, A. Badini, D. Zaccheo (1991)
J. Thorac. Cardiovasc. Surg. 102:440-447
[comment in J Thorac. Cardiovasc. Surg. (1994) 107:948-949]
Monoclonal Antibodies to Type V Collagen for Immunohistological Examination of New Tissue Deposition Associated with Biomaterials Implants
J.A. Werkmeister, J.A.M Ramshaw (1991)
J. Histochem. Cytochem. 39:1215-1220
Structural Stability of Long-Term Implants of a Collagen-Based Vascular Prosthesis
J.A. Werkmeister, V. Glattauer, T.A. Tebb, J.A.M. Ramshaw, G.A. Edwards, G. Roberts (1991)
J. Long Term Eff. Med. Implants 1:107-119
Angiogenesis and Neovascularisation in Different Prosthetic Vascular Grafts: The Significance of Graft Porosity
M.D. Menger, P. Walters, F. Hammersen, K. Messmer (1990)
In Advances in Biomaterials, vol. 9, pp 511-516. Elsevier Science Publishers, Amsterdam, 1990.
Collagen organization in mandrel-grown vascular grafts
J.A.M. Ramshaw, D.E. Peters, J.A. Werkmeister, V. Ketharanathan (1989)
J. Biomed. Mater. Res. 23:649-660
The role of physical and chemical characteristics in assessing the performance of a biological vascular graft
G. Roberts, H. McCormack, V. Ketharanathan, D.G. Macleish, P.L. Field, P.Y. Milne (1989)
J. Biomed. Mater. Res. 23:443-450
In vivo evaluation of four chemically processed biological grafts implanted as infrarenal arterial substitutes in dogs.
Y. Marois, D. Boyer, R. Guidoin, Y. Douville, M. Marois, F.J. Teijeira, P.E. Roy (1989)
Biomaterials 10 :369-379
Histopathological Comparative long term evaluation of reinforced Biosynthetic Ovine collagen Vascular Prostheses with Dardik Human Umbilical Vein Grafts
G.J. Wilson, P. Klement (1988)
Acta of the XXVI World Congress of the International College of Surgeons, Milan, 3-9 July 1988. Ed M. Montorsi. Monduzzi Editore, Bologna (Italy).
The evolution of biological vascular prostheses
D.G. MacLeish, V. Ketharanathan, G. Roberts (1988)
In the Lecture Book, pp 462-463. Eds. M. Montorsi, P. Granelli. 1988 Surgical Updating, First World Postgraduate Surgical Week of the University of Milan and the XXVI World Congress of the International College of Surgeons, Milan, 3-9 July 1988.
Short Communication: The Use of Control Charts in Setting Up Physicochemical Standards for a Biosynthetic Vascular Graft
C. Wadelton, G. Roberts (1987)
Life Support Syst. 5:329-333
Initial experiences with polyester mesh-reinforced ovine fibrocollagenous tubes as arterial xenografts in dogs
M. Friedell, A.J. Villanueva, V. Parsonnet, P. Klement, G.J. Wilson, D.C. MacGregor (1986)
In Progress in Angiology, pp 607-610. Edizine Minerva Medica, Torino.
Properties and Characteristics of Bioprosthetic Grafts
R.E. Baier (1986)
In Vascular Graft Update: Safety and Performance, pp 95-107. Eds. H.E. Kambic, A. Kantrowitz, P. Sung. American Society for Testing and Materials, Philadelphia, 1986.
A comparison of the Dardik biograft with a reinforced ovine collagen tube vascular graft
G.J. Wilson, P. Klement, D.C. MacGregor (1985)
In Progress in Angiology, pp 413-416. Paper presented at the International Congress of Angiology, Athens, 9-14 June 1985. Edizioni Minerva Medica, Torino.
Minute Vascular Replacements
B.A. Christie, V. Ketharanathan, L.J. Perloff (1981)
Arch. Surg. 117:1290-1294
A New Replacement For Small Vessels
L.J. Perloff, B.A. Christie, V. Ketharanathan, P.L. Field, P.Y. Milne, D.G. MacLeish, G. Royal (1981)
Surgery 39:31-41
Glutaraldehyde Tanned Ovine Collagen Compared With Polytetrafluoroethylene (Gore-Tex) As A conduit For Small Calibre Artery Substitution; An Experimental Study In Dogs
V. Ketharanathan, B.A. Christie (1981)
Aust. N.Z. J. Surg. 51:556-561
Glutaraldehyde-Tanned Ovine Collagen Conduits as Vascular Xenografts in Dogs
V. Ketharanathan, B.A. Christie (1980)
Arch. Surg. 115:967-969