Coronary Artery Bypass Graft
Recent advances have demonstrated that, by lining the inside of small diameter engineered tissue tubes with a patient’s own living endothelial cells, a patient specific living blood vessel can been created which may be suitable for coronary artery bypass grafts.
In vitro studies have demonstrated that endothelial cells can be grown on Bio Nova's scaffolds and they remain firmly attached when subjected to physiological flow conditions.
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References
Adherence of human saphenous vein endothelial cell monolayers to tissue-engineered biomatrix vascular conduits
I.E. Birchall, P.L. Field, V. Ketharanathan (2001)
Journal of Biomedical Materials Research 56 (3): 437-443
Retention of endothelium on ovine collagen biomatrix vascular conduits under physiological shear stress
I.E. Birchall, V.W.K Lee, V. Ketharanathan (2001)
Biomaterials 22 (23): 3139-3144